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 GENERIC NAME:- Sirolimus
 COMPANY:- Zydus Cadila
 STRENGTH:- 1 mg
 PACKING:- 1x6
 TYPE:- Tablet
 USES:- Immunosuppressants and vaccines
 Description:-Siromus 1 mg tablet is used in transplant rejection of kidney.It suppresses the activity of body's immune system and prevents rejection of the transplanted organ.
 Expert Advice:-
  • You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin.
  • Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness.
  • Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus.
  • Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped.
  • Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection.
  • Limit the exposure to Sun Pharmalight and UV light by covering your skin with clothing and using a Sun Pharmascreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus.
  • Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.
 Side Effects:-Nausea, Headache, Abdominal pain, Viral infection, Pneumonia, Reduced blood platelets, Increased heart rate, Decreased white blood cell count, Anemia, Urinary tract infection, Diarrhoea, Increased blood pressure, Bacterial infection, Fungal infection, Constipation, Herpes virus infection.

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